I rarely have panic attacks, but I have had quite a few bad trips. But, I've also learned through tripping how to let go and not worry about life. If you are afraid of panicking while tripping, chances are you will panic. But if you do decide to try a psychedlic, just make sure you are in a very good environment and remember that you control your trip. If you want to have a good and insightful trip, then all you have to do is make that happen. It's a bit like lucid dreaming.